Imagine a very long text written by using only 4 letters: A, T, G and C. Three billion of these letters – spread over 23– are linked to one another to form our . This is what constitutes our , our biological identity and the genetic heritage that we pass on to our children.
PARP1:coding for a involved in repair. When it binds with another , HPF1, like two pieces of a jigsaw puzzle that lock to become a different shape, their active sites add up to create a novel one. PARP1 in the presence of HPF1 is still involved in repair but acts differently.
SMIM1:involved in the formation of red blood . A particular of this is associated with a very rare blood group called Vel-negative.
TRNP1: Thisis involved in brain development and the formation of grooves.
TCHH:involved in producing hair. Certain variations of this are associated with frizzy hair.
PM20D1:involved in the regulation of body temperature.
FMO3 : When defective, thisis involved in the release of disagreeable body smells (rotting fish).
SRGAP2 : Thisis involved in brain development and is only found in humans.
BRDT : Thisis involved in making sperm and is an ideal target for male contraception.
ACKR1: Thiscodes for the Duffy blood group . Individuals who do not produce the Duffy FY(A-B-) are more resistant to certain forms of malaria.
VN1R5: Thiscodes for a .
KISS1: If thisis dysfunctional, puberty stalls. A way of staying young?
COX2: Thiscodes for a which is targeted by aspirin.
ApoAII: Thisis involved in the transport of fats in our blood.
CRP: Thiscodes for a which induces repair.
HIST2H4A: This is one of the numerousthat code for histone . The characteristic architecture of a is due to the way is wound around histones.
PDE4B: Thismay be involved in the action of certain kinds of medication (antidepressants, anti-inflammatory drugs).
RSPO1:involved in gender determination.
CNR2: Thiscodes for a which binds to one of the components of cannabis.
TARS1/ TAR1S2/ TAR1S3: Groups ofinvolved in the perception of sweet and umami tastes.