Chromosome 15
Chromosome 15
Length of DNA
101'991'189 bp
i.e. 3.4 cm
Estimated number of genes
612
Sequenced
in Canada, the UK and the USA
Link
The eyes have it
We are all different. Yet our DNA is very similar.
fat administrator
PLIN1: This gene is involved in lipid regulation in our cells.
Endless Smoking
CHRNA5 : one of the genes associated with nicotine dependence. A variation in this gene has also been linked to heavier smoking and a lower likelihood of successfully quitting smoking.
External links
Corresponding protein in UniProtKB/Swiss-Prot
Publication Multiple independent loci at chromosome 15q25.1 affect smoking quantity…
Multitask
FBN1: gene coding for two proteins: 1) fibrillin-1 which is the major component of connective tissue and 2) asprosin, a hormone that is secreted in white adipose tissue and is involved in glucose regulation in the liver, muscles and the pancreas. Variations in this gene are the cause of Marfan syndrome (distorted skeleton).
Scissors and COVID-19
FURIN: This gene codes for a protein that cleaves other proteins. It facilitates human coronavirus SARS-CoV-2 infections by cleaving the coronavirus spike proteins.
External links
Corresponding protein in UniProtKB/Swiss-Prot
creator of networks
HOMER2: This gene codes for a protein which is essential for neuron connection.
molecular breakdown
CYP1A2: This gene is involved in the degradation of certain molecules, such as caffeine.
dear antlers, …
ANXA2: This gene is involved in the regeneration of deer antlers, and is also found in humans!
the colour of skin
SLC24A5: This gene is involved in the synthesis of melanin, a pigment found in our skin, our hair and our iris.
External links
Prolune - snapshot: SLC24A5
Protein Spotlight: Skin deep
Corresponding protein in UniProtKB/Swiss-Prot
one too many…
GABRA: This gene codes for a protein which has an important role in the effects of alcohol.
External links
Prolune - article: In vino veritas
Protein Spotlight: Forbidden fruit
Corresponding protein in UniProtKB/Swiss-Prot