Chromosome 14
Chromosome 14
Length of DNA
107'043'718 bp
i.e. 3.5 cm
Estimated number of genes
819
Sequenced
in France and the USA
Link
+
Chromosome 14 carries many genes which are very important for our immune system.
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Cell profusion
AKT1: Gene involved in the occurrency of outgrowths in certain tissues. Certain variations of this gene influence the effects of cannabis…
External links
Corresponding protein in UniProtKB/Swiss-Prot
contraction
SETD3: Gene coding for a protein which modifies proteins that are required for smooth muscle contraction of the uterus during delivery.
defence
IGHG1: One of the genes that codes for antibodies – an essential part of our immune system.
External links
Corresponding protein in UniProtKB/Swiss-Prot
silencing proteins
DICER1: This gene is involved in regulating the synthesis of certain proteins.
calcium-sensitive
CALM1: This gene encodes calmodulin, which perceives changes of calcium concentration and transmits the information to other proteins.
External links
Prolune – snapshot: Calmodulin
Protein music (in French): Calmodulin
3D story (PDB): Calmodulin
Corresponding protein in UniProtKB/Swiss-Prot
5% hereditary
PDEN1: This gene is associated with Alzheimers disease.
External links
Prolune - article: Alzheimer’s disease: when the mind goes astray
Corresponding protein in UniProtKB/Swiss-Prot
Internal links
Chromosome 12: FKBP4
Churchill
CHURC1: This gene codes for the Churchill protein. It was named after the famous victory V sign made popular by the statesman, which is similar to the shape of the protein. CHURC1 is involved in neuron development.
External links
3D story (PDB): The 3D structure of the Churchill protein
Corresponding protein in UniProtKB/Swiss-Prot
pickle
CN1H1: This gene codes for the cornichon protein which binds to the Gurken protein – Gurken meaning gherkin in German.
External links
Corresponding protein in UniProtKB/Swiss-Prot
turn it down
COCH: This gene is associated with congenital deafness.
External links
Protein Spotlight : The Japanese Horseshoe Crab and Deafness
Corresponding protein in UniProtKB/Swiss-Prot