YTHDF1:coding for a which contains disordered regions, i.e. regions which adopt no particular . These regions are involved in the formation of stress granules – consisting of and mRNA – when a is under some kind of pressure. It is thought that the granules either protect or degrade the mRNA.
There is onewhich is capable of transmitting a disease: the prion .
TGM2:coding for a that changes its conformation according to the environment (e.g. presence of calcium). It is involved in many different biological processes, such as bone development, wound healing, differentiation, chromatin modification and apoptosis. Its multiplicity continues to confound researchers.
ZBP1: Key innate cellular sensor that recognizes and binds to particularstructures called Z- structures, which are produced by a number of viruses as they replicate. Binding of ZBP1 triggers off different forms of death.
PCK1 :coding for a involved in the production of glucose, an important source of energy. In , this activity can be modified to produce that are also a source of energy besides being an essential component of . Tumour that divide rapidly are particularly in need of !
SEMG1/SEMG2: Thesecode for the most abundant in sperm.
ADA: Thismay be involved in sleep.
CPNE1: Thiscodes for copine (meaning ‘friend’ in French), a which binds to .
AVP: Thisis involved in regulating the volume of urine.