Chromosome 22
Chromosome 22
Length of DNA
50'818'468 bp
i.e. 1.7 cm
Estimated number of genes
495
Sequenced
in Australia, Canada, Japan, New Zealand, Sweden, the UK and the USA
Link
+
Chromosome 22 was the first human chromosome to have been sequenced.
My genome, your genome, their genome… and then what?
The human genome was sequenced in 2000. The news broke as though we had just unravelled the mystery of human life. Yet, we still know very little.
anti-arsenic
AS3MT: gene coding for a protein that modifies arsenic and makes it less toxic. Adaptation to arsenic serves as a model for how organisms evolve to survive under toxic conditions.
External links
Corresponding protein in UniProtKB/Swiss-Prot
Expresso
ADORA2A: a gene that determines whether a person is highly or low sensitive to caffeine, meaning how much caffeine you should take before it has invigorating effects.
antiviral
APOBEC3G: Gene involved in antiviral defense.
Smurfs
CYB5R3: gene coding for a protein that is involved in the redox of iron atoms in hemoglobin. Variations in this gene are associated with hemoglobin that binds oxygen less efficiently. Carriers have bluish (cyanotic) skin.
External links
Corresponding protein in UniProtKB/Swiss-Prot
autism
SHANK3: This gene is associated with autism.
molecular degradation
CYP2D6: This gene is involved in neutralising toxic products and certain drugs.
External links
Corresponding protein in UniProtKB/Swiss-Prot
epilepsy
TEF: This gene may be involved in epilepsy. The gene was discovered by the cleaning staff while vacuuming the animal care facilities at the University of Geneva!
External links
Prolune - snapshot: The PAR bZIP family
a taxi for oxygen
MB: This gene is involved in oxygen transport in our muscles.
Internal links
Chromosome 11: HBB
seeing more clearly
CRYBA4/CRYBB2: These genes are involved in the lens structure of our eyes.
External links
Corresponding protein in UniProtKB/Swiss-Prot
creator of networks
RTN4R: This gene hinders neuronal growth and helps them to branch out.
External links
Protein Spotlight: Nerve regrowth: nipped by a no-go
Corresponding protein in UniProtKB/Swiss-Prot