Chromosome 5
Chromosome 5
Length of DNA
181'538'259 bp
i.e. 6.0 cm
Estimated number of genes
884
Sequenced
in the USA
Link
Gene…Where are you?
DNA, like the genes it carries, forms the basis for life. There is not one living organism on this planet that doesn’t have DNA. Hence, the better we get to know DNA – and its genes in their smallest detail – the better we will understand how life is made.
Black Death
ERAP2: variations in this gene are associated with increased resistance to infection with Yersinia pestis, a bacterium responsible for the Black Death that occurred in the mid-14th century. These variations could be associated today with a greater susceptibility to develop an autoimmune disease.
External links
Corresponding protein in UniProtKB/Swiss-Prot
Publication: Evolution of immune genes is associated with the Black Death
stress
DELE1 : Gene coding for a protein which can be seen as a messenger capable of relaying a stress signal from the mitochondrion to the cell. This ‘integrated stress response’ indicates to the cell that mitochondria need help, and the cell will do its best to fix the situation.
protrusion
CDHR2: Gene coding for a protein involved in the formation of microvilli on the surface of some epithelial cells.
Help !
DELE1 : key activator of the integrated stress response following mitochondrial problems. This indicates to the cell that mitochondria need help, and the cell will do its best to fix the situation.
skin colour
SLC45A2: Gene involved in the synthesis of melanin, a pigment found in our skin, our hair and the iris of our eyes.
External links
Corresponding protein in UniProtKB/Swiss-Prot
remembering to forget
RGS14: This gene is involved in memory and forgetfulness. The act of forgetting helps to keep our memory unburdened.
silencing proteins
DROSHA: This gene is involved in regulating the synthesis of certain proteins.
glue for our tissues
CDH6: This gene is involved in cell adhesion, which is essential in tissues.
External links
Corresponding protein in UniProtKB/Swiss-Prot
glue for our tissues
PCDH: Group of over 60 genes involved in cell adhesion, which is essential in tissues.
External links
One of the corresponding proteins in UniProtKB/Swiss-Prot
on the edge of madness
GABRB2/GABRA1/GABRA6/GABRG2: Groups of genes involved in the harmful effects of absinthe consumption.
External links
Protein Spotlight: Forbidden fruit
One of the corresponding proteins in UniProtKB/Swiss-Prot
defence
IL3: This gene is involved in the production of white blood cells.
External links
Corresponding protein in UniProtKB/Swiss-Prot