Chromosome 13
Chromosome 13
Length of DNA
114'364'328 bp
i.e. 3.8 cm
Estimated number of genes
321
Sequenced
in the UK
Link
A taste of happiness
For many, chocolate offers brief moments of pleasure that we like to enjoy over and over again. Why?
haemophilia
F10: This gene is important in blood coagulation, and is associated with certain forms of haemophilia.
External links
Corresponding protein in UniProtKB/Swiss-Prot
polymers
ACOD1: this gene codes for a protein that catalyzes the production of itaconate. Itaconate is widely used in the synthesis of polymers to make lubricants, thickeners, rubber or resins. Itaconate is also involved in the inhibition of inflammatory response and in antimicrobial response.
turn it down
GJB2: Gene associated with congenital deafness.
External links
Corresponding protein in UniProtKB/Swiss-Prot
out of the ordinary
SLITRK1: Gene involved in neuronal dendrite outgrowth. Mutations in this gene are associated with Tourette Syndrome, a neuropsychiatric disorder.
defence
TNFSF13B: This gene codes for a cytokine, an important molecule in the immune response.
External links
Corresponding protein in UniProtKB/Swiss-Prot
don’t worry, be happy…
DAOA: This gene is involved in producing a molecule which interacts with the ‘happy receptor’. This part of the chromosome is associated with psychiatric disorders such as schizophrenia.
External links
Corresponding protein in UniProtKB/Swiss-Prot
a taxi for copper
ATO7B: This gene is involved in copper transport, and is essential for the correct functioning of many enzymes.
External links
Corresponding protein in UniProtKB/Swiss-Prot
a longer life
KL: This gene codes for the klotho protein which seems to be involved in longevity.
cellular abundance
BRCA2: This gene is involved in cell proliferation and is associated with breast cancer.
External links
Corresponding protein in UniProtKB/Swiss-Prot