This discovery shattered a century-old scientific concept. Until then, microbes were thought to be the only biological entities able to cause an infection. While viruses, fungi andinfect us by multiplying in our body, prions cause infection by changing shape.
For unknown reasons, prions become infectious by changing their shape and hence their humour, just like Dr Jekyll and Mr Hyde.
Abnormal prioncontaminate an organism by forcing healthy prion to take on the infectious shape. This is a novel way of causing infection. Indeed, abnormal prion are neither viruses nor , yet they are able to spread from one organism to another, and from one species to another. It is a revolutionary discovery!