For a long time, the dogma was: one , one . However, over the years, it became apparent that a can in fact give rise to more than one . This is precisely one of the phenomenona that the realm of is unable to predict. Nature will always prove to be more complex than we imagine.
It was the case for thewhich gives rise to two small : ghrelin and obestatin. programs had been unable to predict their separate existence! Indeed, tools detected only one whereas, in the laboratory, scientists discovered that the otherwise inactive was actually split into two smaller which in turn became active.
Ghrelin and obestatin are involved in controlling our appetite. Ghrelin gives out hunger signals while obestatin tells us when we have had enough to eat. These are sensations that we take for granted simply because they seem so natural to us. However, it is important for our body to be able to differentiate between ‘hungry’ and ‘no longer hungry’.
If for some reason the ghrelin/obestatin balance is lost, our body tends towards obesity or, on the contrary, anorexia. However, feelings of hunger and satiation are not only under the influence of. They are also guided by our emotions and dietary habits. It is a very sophisticated system which depends on many factors – from physiological to psychological and cultural.
One of the first descriptions of obesity and possible surgical intervention dates back to the 3rd century AD!