Chromosome 9
Chromosome 9
Length of DNA
138'394'717 bp
i.e. 4.7 cm
Estimated number of genes
780
Sequenced
in Germany and the UK
Link
Art and bioinformatics
Artists have always found inspiration in science. And art is singular in that it can make science more human by shedding light on the beauty and elegance of the tiny world we are made out of.
pace
DMRT3: gene involved in movement coordination. In some horses, this same gene plays a role in the animal’s ability to perform certain types of trots, what is known as the pace.
External links
Protein Spotlight : a gait on the wildside
Corresponding protein in UniProtKB/Swiss-Prot
Rupture and apoptosis
NINJ1: Gene coding for a protein that mediates plasma membrane rupture during apoptosis (programmed cell death).
External links
Corresponding protein in UniProtKB/Swiss-Prot
Protein Spotlight: Rupture
Protein Spotlight: Cutting edges
Dormant ribosomes
HABP4: A ribosome-associated protein that facilitates ribosome hibernation—a process that stabilizes ribosomes in an inactive state during conditions such as nutrient deprivation, osmotic stress, temperature shock, or gametogenesis.
anti-COVID19 target?
CTSL: gene coding for a protein that facilitates coronavirus SARS-CoV and SARS-CoV-2 infection via the cleavage of the coronavirus spike protein. CTSL is the target of potential anti-COVID19 drugs.
External links
Corresponding protein in UniProtKB/Swiss-Prot
Neurons and testicles
TMEFF1 protects neurons against herpes virus infection. This protein is found not only in neurons, but also in the testicles!
repair
XPA : this gene is involved in DNA repair. The system, however, is not perfect. As a result, a few mistakes are kept and turn out to be indispensable for the evolution of the species.
nickel
TLR4: This gene may be involved in nickel allergies.
External links
Protein Spotlight : zips, necklaces and mobile telephones
Corresponding protein in UniProtKB/Swiss-Prot
une histoire de soutien
COL5A1: Gène codant pour un type de collagène, protéine abondante dans les os, la peau et les cartilages.
A, B, AB ou O ?
ABO: Gene with variations responsible for determining our blood group – A, AB, B or O.
a passage for water
AQP3: This gene codes for a protein – aquaporin – that acts as a channel for ferrying water molecules throughout our body.
External links
Prolune – snapshot: Aquaporin
Prolune - article: Aquaporins: «A Nobel Prize for the water ferries»
Prolune - play (PDF): «AquaWhat ?»
3D video (NIH resource) : Download movie 13.1M
Protein Spotlight: Liquid states
Corresponding protein in UniProtKB/Swiss-Prot
Internal links
Chromosome 7: AQP1
treatment of multiple sclerosis
IFNB1: Gene coding for interferon beta, a protein used in the treatment of multiple sclerosis.
External links
Prolune - dossier : Protéine phare contre la sclérose en plaques Corresponding protein in UniProtKB/Swiss-Prottesticular architect
DMRT1: This gene could be involved in the development of testicles in many species – ranging from mammals to reptiles, including birds.
External links
Corresponding protein in UniProtKB/Swiss-Prot