Chromosome 12
Anti-COVID-19
https://www.chromosomewalk.ch/en/chromosome/chromosome-12/anti-covid-19/
OAS1: Gene involved in the fight against certain viral infections. A variant of this gene, inherited from Neanderthal, is thought to give protection against COVID-19.
Chromosome 3
COVID-19 and Neanderthals
https://www.chromosomewalk.ch/en/chromosome/chromosome-3/covid-19-and-neanderthals/
Publication: The major genetic risk factor for severe COVID-19 is inherited from Neanderthals
Chromosome 21
Scissors, prostate and COVID-19
https://www.chromosomewalk.ch/en/chromosome/chromosome-21/prostate-and-covid-19/
TMPRSS2: This gene codes for a protein that cleaves proteins involved in prostate physiological function. Facilitates human coronavirus SARS-CoV-2 infections via the proteolytic cleavage of ACE2 and coronavirus spike proteins.
Chromosome 15
Scissors and COVID-19
https://www.chromosomewalk.ch/en/chromosome/chromosome-15/scissors-and-covid-19/
FURIN: This gene codes for a protein that cleaves other proteins. It facilitates human coronavirus SARS-CoV-2 infections by cleaving the coronavirus spike proteins.
Chromosomes xx
Gender and COVID-19
https://www.chromosomewalk.ch/en/chromosome/chromosomes-xx/gender-and-covid-19/
TLR7: Gene involved in the fight against certain viral infections. Located on the X chromosome, this gene could explain in part the fact that males (who only have one copy of the X chromosome) have a greater risk of hospitalization and mortality than females when infected with SARS-CoV-2.
Chromosome 7
Cytokine storm
https://www.chromosomewalk.ch/en/chromosome/chromosome-7/cytokine-storm/
IL6: a gene coding for a protein that is believed thought to play an important role in the disruption of the immune response, leading to a so-called ‘cytokine storm’, which worsens the condition of patients with COVID-19.